UPLC-MS/MS Method for the Determination of Hyperoside and Application to Pharmacokinetics Study in Rat After Different Administration Routes

A rapid and sensitive UPLC-MS/MS method was developed and fully validated for the quantification of hyperoside in rat plasma after intragastric, intraperitoneal and intravenous administration. Geniposide was used as an internal standard, and simple liquid–liquid extraction by ethyl acetate was utili...

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Detalles Bibliográficos
Autores principales: Yuan, Wenjing, Wang, Jingjing, An, Xiaofei, Dai, Mingxin, Jiang, Zhenzhou, Zhang, Luyong, Yu, Sen, Huang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810192/
https://www.ncbi.nlm.nih.gov/pubmed/33487663
http://dx.doi.org/10.1007/s10337-020-04002-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810192/
https://www.ncbi.nlm.nih.gov/pubmed/33487663
http://dx.doi.org/10.1007/s10337-020-04002-x

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