Cargando…

UPLC-MS/MS Method for the Determination of Hyperoside and Application to Pharmacokinetics Study in Rat After Different Administration Routes

A rapid and sensitive UPLC-MS/MS method was developed and fully validated for the quantification of hyperoside in rat plasma after intragastric, intraperitoneal and intravenous administration. Geniposide was used as an internal standard, and simple liquid–liquid extraction by ethyl acetate was utili...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Wenjing, Wang, Jingjing, An, Xiaofei, Dai, Mingxin, Jiang, Zhenzhou, Zhang, Luyong, Yu, Sen, Huang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810192/ https://www.ncbi.nlm.nih.gov/pubmed/33487663 http://dx.doi.org/10.1007/s10337-020-04002-x

Ejemplares similares

Pharmacokinetics and metabolism of icaritin in rats by UPLC‐MS/MS
por: Huang, Zhen‐Wu, et al.
Publicado: (2019)

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Determined by UPLC-MS/MS
por: Chang, Li-Wen, et al.
Publicado: (2013)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Determination of Tenacissoside G, Tenacissoside H, and Tenacissoside I in Rat Plasma by UPLC-MS/MS and Their Pharmacokinetics
por: Chen, Fan, et al.
Publicado: (2023)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Determination of Bioactive Components in Chinese Herbal Formulae and Pharmacokinetics of Rhein in Rats by UPLC-MS/MS
por: Hou, Mei-Ling, et al.
Publicado: (2014)

Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies
por: Chen, Mengchun, et al.
Publicado: (2020)

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
por: Liu, Pei, et al.
Publicado: (2022)

Pharmacokinetic Study of Delavinone in Mice after Intravenous and Oral Administration by UPLC-MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2019)

Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics
por: Su, Yan-Ding, et al.
Publicado: (2022)

Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract
por: Xu, Zhan-Ling, et al.
Publicado: (2018)

Pharmacokinetic Study of Thirteen Ingredients after the Oral Administration of Flos Chrysanthemi Extract in Rats by UPLC-MS/MS
por: Jia, Qi, et al.
Publicado: (2020)

UPLC-MS/MS Measurement of the Effect of Isavuconazole, Itraconazole and Fluconazole on the Pharmacokinetics of Selinexor in Rats
por: Li, Shuang-long, et al.
Publicado: (2020)

Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application
por: Li, Shuang-long, et al.
Publicado: (2020)

Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability
por: He, Yan, et al.
Publicado: (2022)

Development of a UPLC-MS/MS method for the determination of orelabrutinib in rat plasma and its application in pharmacokinetics
por: Liu, Ya-nan, et al.
Publicado: (2022)

Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS
por: Li, Heng, et al.
Publicado: (2022)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Systematic Identification, Fragmentation Pattern, And Metabolic Pathways of Hyperoside in Rat Plasma, Urine, And Feces by UPLC-Q-Exactive Orbitrap MS
por: Ji, Li, et al.
Publicado: (2022)

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood
por: Shao, Lingjiu, et al.
Publicado: (2018)

Comparative Pharmacokinetics of Cinobufacini Capsule and Injection by UPLC-MS/MS
por: Li, Ming, et al.
Publicado: (2022)

Plasma Pharmacokinetic Determination of Canagliflozin and Its Metabolites in a Type 2 Diabetic Rat Model by UPLC-MS/MS
por: Dong, Song-tao, et al.
Publicado: (2018)

Determination and pharmacokinetic analysis of ticarcillin disodium–clavulanate potassium for injection in rat plasma by UPLC-ESI-MS/MS
por: Wang, Moli, et al.
Publicado: (2020)

Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma
por: Zhang, En, et al.
Publicado: (2021)

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS
por: Zheng, Xiang, et al.
Publicado: (2017)

Pharmacokinetics of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, in Rats by UPLC-MS/MS
por: Wang, Bo, et al.
Publicado: (2020)

UPLC-MS/MS Technology for the Quantitative Methodology and Pharmacokinetic Analysis of Voxtalisib in Rat Plasma
por: Li, Qingqing, et al.
Publicado: (2022)

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2023)

An UPLC-MS/MS Method for Determination of Osimertinib in Rat Plasma: Application to Investigating the Effect of Ginsenoside Rg3 on the Pharmacokinetics of Osimertinib
por: Ying, Zhenzhen, et al.
Publicado: (2020)

Simultaneous determination of phenolic acids by UPLC–MS/MS in rat plasma and its application in pharmacokinetic study after oral administration of Flos Lonicerae preparations
por: Zhou, Wei, et al.
Publicado: (2013)

Pharmacokinetic and excretion study of three alkaloids in rats using UPLC-MS/MS after oral administration of menispermi rhizoma capsules
por: Yu, Jia, et al.
Publicado: (2018)

Multi-component pharmacokinetic study of prunus mume fructus extract after oral administration in rats using UPLC-MS/MS
por: Zhu, Yameng, et al.
Publicado: (2022)

Determination of total and unbound docetaxel in plasma by ultrafiltration and UPLC-MS/MS: application to pharmacokinetic studies
por: Sheu, Ming-Thau, et al.
Publicado: (2017)

Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS
por: Sun, Chengtao, et al.
Publicado: (2017)

Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study
por: Wang, Shixiao, et al.
Publicado: (2017)

A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study
por: He, Long, et al.
Publicado: (2019)

Pharmacokinetic Comparisons of Different Combinations of Yigan Jiangzhi Formula in Rats: Simultaneous Determination of Fourteen Components by UPLC-MS/MS
por: Wang, Yang, et al.
Publicado: (2020)

Eco-Friendly UPLC–MS/MS Method for Determination of a Fostamatinib Metabolite, Tamatinib, in Plasma: Pharmacokinetic Application in Rats
por: Ezzeldin, Essam, et al.
Publicado: (2021)

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
por: Ma, Weina, et al.
Publicado: (2019)

Development of UPLC-MS/MS Method for Studying the Pharmacokinetic Interaction Between Dasatinib and Posaconazole in Rats
por: Yang, Suili, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3up08av3v6merjdim9omtq7mfj