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Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride
We report a mild method for the selective deprotection of the N-Boc group from a structurally diverse set of compounds, encompassing aliphatic, aromatic, and heterocyclic substrates by using oxalyl chloride in methanol. The reactions take place under room temperature conditions for 1–4 h with yields...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810210/ https://www.ncbi.nlm.nih.gov/pubmed/33456769 http://dx.doi.org/10.1039/d0ra04110f |