Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors

BACKGROUND: In Central and South America, snakebite envenomation is mainly caused by Bothrops spp. snakes, whose venoms feature significant biochemical richness, including serine proteases. The available bothropic antivenoms are efficient in avoiding fatalities, but do not completely neutralize veno...

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Detalles Bibliográficos
Autores principales: da Silva, Gloria Maria, de Souza, Daniel Henrique Berto, Waitman, Karoline B., Ebram, Matteo Celano, Fessel, Melissa R., Zainescu, Iuliu Cezar, Portaro, Fernanda C., Heras, Montse, de Andrade, Sonia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810238/
https://www.ncbi.nlm.nih.gov/pubmed/33488681
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810238/
https://www.ncbi.nlm.nih.gov/pubmed/33488681
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0066

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