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The Rab32/BLOC-3–dependent pathway mediates host defense against different pathogens in human macrophages

Macrophages provide a first line of defense against microorganisms, and while some mechanisms to kill pathogens such as the oxidative burst are well described, others are still undefined or unknown. Here, we report that the Rab32 guanosine triphosphatase and its guanine nucleotide exchange factor BL...

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Detalles Bibliográficos
Autores principales: Baldassarre, Massimiliano, Solano-Collado, Virtu, Balci, Arda, Colamarino, Rosa A., Dambuza, Ivy M., Reid, Delyth M., Wilson, Heather M., Brown, Gordon D., Mukhopadhyay, Subhankar, Dougan, Gordon, Spanò, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810368/
https://www.ncbi.nlm.nih.gov/pubmed/33523895
http://dx.doi.org/10.1126/sciadv.abb1795