Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors

The mechanical challenge of attaching elastic tendons to stiff bones is solved by the formation of a unique transitional tissue. Here, we show that murine tendon-to-bone attachment cells are bi-fated, activating a mixture of chondrocyte and tenocyte transcriptomes, under regulation of shared regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kult, Shiri, Olender, Tsviya, Osterwalder, Marco, Markman, Svetalana, Leshkowitz, Dena, Krief, Sharon, Blecher-Gonen, Ronnie, Ben-Moshe, Shani, Farack, Lydia, Keren-Shaul, Hadas, Salame, Tomer-Meir, Capellini, Terence D, Itzkovitz, Shalev, Amit, Ido, Visel, Axel, Zelzer, Elazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810463/
https://www.ncbi.nlm.nih.gov/pubmed/33448926
http://dx.doi.org/10.7554/eLife.55361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810463/
https://www.ncbi.nlm.nih.gov/pubmed/33448926
http://dx.doi.org/10.7554/eLife.55361

Ejemplares similares