Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis–infected lungs

Correlative light, electron, and ion microscopy (CLEIM) offers huge potential to track the intracellular fate of antibiotics, with organelle-level resolution. However, a correlative approach that enables subcellular antibiotic visualisation in pathogen-infected tissue is lacking. Here, we developed...

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Detalles Bibliográficos
Autores principales: Fearns, Antony, Greenwood, Daniel J., Rodgers, Angela, Jiang, Haibo, Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810513/
https://www.ncbi.nlm.nih.gov/pubmed/33382684
http://dx.doi.org/10.1371/journal.pbio.3000879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810513/
https://www.ncbi.nlm.nih.gov/pubmed/33382684
http://dx.doi.org/10.1371/journal.pbio.3000879

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