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lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration

The phenotypic switch in tumor-associated macrophages (TAMs) mediates immunity escape of cancer. However, the underlying mechanisms in the TAM phenotypic switch have not been systematically elucidated. In this study, long noncoding RNA (lncRNA)-Xist, CCAAT/enhancer-binding protein (C/EBP)α, and Krup...

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Detalles Bibliográficos
Autores principales: Zhao, Yanyun, Yu, Zhaojin, Ma, Rong, Zhang, Yifan, Zhao, Lin, Yan, Yuanyuan, Lv, Xuemei, Zhang, Liwen, Su, Panpan, Bi, Jia, Xu, Hong, He, Miao, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810606/
https://www.ncbi.nlm.nih.gov/pubmed/33510942
http://dx.doi.org/10.1016/j.omtn.2020.12.005