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Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells

BACKGROUND: Cancer cells could show the characteristics of cancer stem cells (CSCs) through epithelial-mesenchymal transition (EMT). EZH2 was associated with EMT. Ultrasound-targeted microbubble destruction (UTMD) could enhance gene transfection efficiency. Here, we explored the effect of UTMD-media...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Sun, Lulu, Liu, Tingting, Dong, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810681/
https://www.ncbi.nlm.nih.gov/pubmed/33469303
http://dx.doi.org/10.2147/OTT.S269589