Cargando…

Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells

BACKGROUND: Cancer cells could show the characteristics of cancer stem cells (CSCs) through epithelial-mesenchymal transition (EMT). EZH2 was associated with EMT. Ultrasound-targeted microbubble destruction (UTMD) could enhance gene transfection efficiency. Here, we explored the effect of UTMD-media...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jie, Sun, Lulu, Liu, Tingting, Dong, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810681/ https://www.ncbi.nlm.nih.gov/pubmed/33469303 http://dx.doi.org/10.2147/OTT.S269589

Ejemplares similares

Ultrasound targeted microbubble destruction-mediated SOCS3 attenuates biological characteristics and epithelial-mesenchymal transition (EMT) of breast cancer stem cells
por: Tang, Xiaojiang, et al.
Publicado: (2022)

A combination of ultrasound-targeted microbubble destruction with transplantation of bone marrow mesenchymal stem cells promotes recovery of acute liver injury
por: Sun, Ting, et al.
Publicado: (2018)

Ultrasound-targeted microbubble destruction optimized HGF-overexpressing bone marrow stem cells to repair fibrotic liver in rats
por: Sun, Ting, et al.
Publicado: (2020)

Kidney-Targeted Transplantation of Mesenchymal Stem Cells by Ultrasound-Targeted Microbubble Destruction Promotes Kidney Repair in Diabetic Nephropathy Rats
por: Zhang, Yi, et al.
Publicado: (2013)

Protein Expression of Mesenchymal Stem Cells after Transfection of pcDNA3.1(−)-hVEGF(165) by Ultrasound-Targeted Microbubble Destruction
por: Pu, Zhaoxia, et al.
Publicado: (2011)

Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats
por: Wu, Shengzheng, et al.
Publicado: (2014)

Augmentation of transgenic expression by ultrasound-mediated liposome microbubble destruction
por: CHEN, ZHI-YI, et al.
Publicado: (2012)

Using ultrasound-targeted microbubble destruction to enhance radiotherapy of glioblastoma
por: Peng, Chanjuan, et al.
Publicado: (2021)

PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1
por: Qi, Yanmei, et al.
Publicado: (2020)

Casticin inhibits epithelial-mesenchymal transition of liver cancer stem cells of the SMMC-7721 cell line through downregulating Twist
por: HE, MENG, et al.
Publicado: (2014)

Ultrasound-targeted microbubble destruction for chemotherapeutic drug delivery to solid tumors
por: Chen, Hong, et al.
Publicado: (2013)

Selective depletion of tumor neovasculature by microbubble destruction with appropriate ultrasound pressure
por: Wang, Junfen, et al.
Publicado: (2015)

Ultrasound-mediated microbubble destruction: a new method in cancer immunotherapy
por: Tu, Jiawei, et al.
Publicado: (2018)

Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study
por: Cui, Hai, et al.
Publicado: (2017)

Ultrasound-Targeted Microbubble Destruction (UTMD) Combined with Liposome Increases the Effectiveness of Suppressing Proliferation, Migration, Invasion, and Epithelial- Mesenchymal Transition (EMT) via Targeting Metadherin (MTDH) by ShRNA
por: Xu, Juan, et al.
Publicado: (2019)

EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells
por: Cardenas, Horacio, et al.
Publicado: (2016)

Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study
por: Li, Lu, et al.
Publicado: (2015)

Ultrasound-targeted microbubble destruction-mediated Galectin-7-siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate acute myocardial infarction in rats
por: Wei, Xin, et al.
Publicado: (2021)

Docetaxel-loaded lipid microbubbles combined with ultrasound-triggered microbubble destruction for targeted tumor therapy in MHCC-H cells
por: Zhang, Yue, et al.
Publicado: (2016)

Effect of Gambogic Acid–Loaded Porous-Lipid/PLGA Microbubbles in Combination With Ultrasound-Triggered Microbubble Destruction on Human Glioma
por: Wang, Feng, et al.
Publicado: (2021)

New Progress in Angiogenesis Therapy of Cardiovascular Disease by Ultrasound Targeted Microbubble Destruction
por: Liao, Yang-Ying, et al.
Publicado: (2014)

Efficient exosome delivery in refractory tissues assisted by ultrasound-targeted microbubble destruction
por: Sun, Wenqi, et al.
Publicado: (2019)

Ultrasound-Targeted Microbubble Destruction: Modulation in the Tumor Microenvironment and Application in Tumor Immunotherapy
por: Han, Ye, et al.
Publicado: (2022)

Use of Nitric Oxide Donor-Loaded Microbubble Destruction by Ultrasound in Thrombus Treatment
por: Corro, Ricardo, et al.
Publicado: (2022)

Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect
por: Liu, Senbo, et al.
Publicado: (2022)

Treatment of glaucomatous optic nerve damage using ginsenoside Rg1 mediated by ultrasound targeted microbubble destruction
por: Wang, Lianfeng, et al.
Publicado: (2018)

Ultrasound-targeted microbubble destruction-mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer
por: Cheng, Li, et al.
Publicado: (2021)

Myocardium-targeted transplantation of PHD2 shRNA-modified bone mesenchymal stem cells through ultrasound-targeted microbubble destruction protects the heart from acute myocardial infarction
por: Sun, Zhenxing, et al.
Publicado: (2020)

Ultrasound-Targeted Microbubble Destruction-Mediated Inhibition of Livin Expression Accelerates Ovarian Cancer Cell Apoptosis
por: Xu, Xiaolin, et al.
Publicado: (2021)

Ultrasound targeted microbubble destruction-triggered nitric oxide release via nanoscale ultrasound contrast agent for sensitizing chemoimmunotherapy
por: Zhao, Yading, et al.
Publicado: (2023)

Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells
por: Takano, Chika, et al.
Publicado: (2022)

EGFP gene transfection into the synovial joint tissues of rats with rheumatoid arthritis by ultrasound-mediated microbubble destruction
por: JING, XIANG-XIANG, et al.
Publicado: (2014)

Myocardium-targeted transplantation of PHD2 shRNA-modified bone mesenchymal stem cells through ultrasound-targeted microbubble destruction protects the heart from acute myocardial infarction: Erratum
por: Sun, Zhenxing, et al.
Publicado: (2022)

Ultrasound‐targeted microbubble destruction mediates PDE5i/NO integration for cavernosum remodeling and penile rehabilitation
por: Yang, Wende, et al.
Publicado: (2023)

Ultrasound with microbubbles
por: Harvey, Chris
Publicado: (2015)

Mesenchymal Stem Cell Transplantation Enhancement in Myocardial Infarction Rat Model under Ultrasound Combined with Nitric Oxide Microbubbles
por: Tong, Jiayi, et al.
Publicado: (2013)

Ultrasound Targeted Microbubble Destruction Stimulates Cellular Endocytosis in Facilitation of Adeno-Associated Virus Delivery
por: Jin, Li-Fang, et al.
Publicado: (2013)

Unilateral Opening of Rat Blood-Brain Barrier Assisted by Diagnostic Ultrasound Targeted Microbubbles Destruction
por: Xu, Yali, et al.
Publicado: (2016)

Delivery of Hydrogen Sulfide by Ultrasound Targeted Microbubble Destruction Attenuates Myocardial Ischemia-reperfusion Injury
por: Chen, Gangbin, et al.
Publicado: (2016)

Ultrasound-targeted microbubble destruction in gene therapy: A new tool to cure human diseases
por: Wu, Jun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8hlgo14p4ctv6te47sktalnrs4