Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice

Spinal cord injury (SCI) often causes severe and permanent disabilities due to the regenerative failure of severed axons. Here we report significant locomotor recovery of both hindlimbs after a complete spinal cord crush. This is achieved by the unilateral transduction of cortical motoneurons with a...

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Detalles Bibliográficos
Autores principales: Leibinger, Marco, Zeitler, Charlotte, Gobrecht, Philipp, Andreadaki, Anastasia, Gisselmann, Günter, Fischer, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810685/
https://www.ncbi.nlm.nih.gov/pubmed/33452250
http://dx.doi.org/10.1038/s41467-020-20112-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810685/
https://www.ncbi.nlm.nih.gov/pubmed/33452250
http://dx.doi.org/10.1038/s41467-020-20112-4

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