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Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B

Clostridioides difficile infection (CDI) has a serious impact on the healthcare system, and most of its pathogenic effects are mainly due to the activity of toxins A and B (TcdA and TcdB, respectively). The molecular mechanisms of their cytotoxic activity are well known, especially in the colon, whe...

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Detalles Bibliográficos
Autores principales: Fettucciari, Katia, Fruganti, Alessandro, Marchegiani, Andrea, Brancorsini, Stefano, Marconi, Pierfrancesco, Bassotti, Gabrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810702/
https://www.ncbi.nlm.nih.gov/pubmed/33469335
http://dx.doi.org/10.2147/JIR.S287096