Cargando…
Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B
Clostridioides difficile infection (CDI) has a serious impact on the healthcare system, and most of its pathogenic effects are mainly due to the activity of toxins A and B (TcdA and TcdB, respectively). The molecular mechanisms of their cytotoxic activity are well known, especially in the colon, whe...
Autores principales: | Fettucciari, Katia, Fruganti, Alessandro, Marchegiani, Andrea, Brancorsini, Stefano, Marconi, Pierfrancesco, Bassotti, Gabrio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810702/ https://www.ncbi.nlm.nih.gov/pubmed/33469335 http://dx.doi.org/10.2147/JIR.S287096 |
Ejemplares similares
-
The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses
por: Bassotti, Gabrio, et al.
Publicado: (2020) -
Cytotoxic synergism of Clostridioides difficile toxin B with proinflammatory cytokines in subjects with inflammatory bowel diseases
por: Bassotti, Gabrio, et al.
Publicado: (2023) -
Clostridioides difficile toxin B alone and with pro-inflammatory cytokines induces apoptosis in enteric glial cells by activating three different signalling pathways mediated by caspases, calpains and cathepsin B
por: Fettucciari, Katia, et al.
Publicado: (2022) -
Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network
por: Bassotti, Gabrio, et al.
Publicado: (2021) -
Invisible steps for a global endemy: molecular strategies adopted by Clostridioides difficile
por: Fettucciari, Katia, et al.
Publicado: (2021)