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Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance

Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle disorders and type 2 diabetes. However, there is currently no clinically effective myostatin inhibitor, and therefore novel methods are required. We evaluated the use of an...

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Detalles Bibliográficos
Autores principales: Eilers, Wouter, Cleasby, Mark, Foster, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810755/
https://www.ncbi.nlm.nih.gov/pubmed/33452345
http://dx.doi.org/10.1038/s41598-021-81222-7