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Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance
Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle disorders and type 2 diabetes. However, there is currently no clinically effective myostatin inhibitor, and therefore novel methods are required. We evaluated the use of an...
Autores principales: | Eilers, Wouter, Cleasby, Mark, Foster, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810755/ https://www.ncbi.nlm.nih.gov/pubmed/33452345 http://dx.doi.org/10.1038/s41598-021-81222-7 |
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