Weighted gene coexpression network and experimental analyses identify lncRNA SPRR2C as a regulator of the IL-22-stimulated HaCaT cell phenotype through the miR-330/STAT1/S100A7 axis

Psoriasis is a chronic inflammatory disease of the skin with highly complex pathogenesis. In this study, we identified lncRNA SPRR2C (small proline-rich protein 2C) as a hub gene with a critical effect on the pathogenesis of psoriasis and response to treatment using both weighted gene coexpression n...

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Detalles Bibliográficos
Autores principales: Luo, Meijunzi, Huang, Pan, Pan, Yi, Zhu, Zhu, Zhou, Rong, Yang, Zhibo, Wang, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810847/
https://www.ncbi.nlm.nih.gov/pubmed/33452236
http://dx.doi.org/10.1038/s41419-020-03305-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810847/
https://www.ncbi.nlm.nih.gov/pubmed/33452236
http://dx.doi.org/10.1038/s41419-020-03305-z

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