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The p63 C-terminus is essential for murine oocyte integrity

The transcription factor p63 mediates distinct cellular responses, primarily regulating epithelial and oocyte biology. In addition to the two amino terminal isoforms, TAp63 and ΔNp63, the 3’-end of p63 mRNA undergoes tissue-specific alternative splicing that leads to several isoforms, including p63α...

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Detalles Bibliográficos
Autores principales: Lena, Anna Maria, Rossi, Valerio, Osterburg, Susanne, Smirnov, Artem, Osterburg, Christian, Tuppi, Marcel, Cappello, Angela, Amelio, Ivano, Dötsch, Volker, De Felici, Massimo, Klinger, Francesca Gioia, Annicchiarico-Petruzzelli, Margherita, Valensise, Herbert, Melino, Gerry, Candi, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810856/
https://www.ncbi.nlm.nih.gov/pubmed/33452256
http://dx.doi.org/10.1038/s41467-020-20669-0