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The p63 C-terminus is essential for murine oocyte integrity
The transcription factor p63 mediates distinct cellular responses, primarily regulating epithelial and oocyte biology. In addition to the two amino terminal isoforms, TAp63 and ΔNp63, the 3’-end of p63 mRNA undergoes tissue-specific alternative splicing that leads to several isoforms, including p63α...
Autores principales: | Lena, Anna Maria, Rossi, Valerio, Osterburg, Susanne, Smirnov, Artem, Osterburg, Christian, Tuppi, Marcel, Cappello, Angela, Amelio, Ivano, Dötsch, Volker, De Felici, Massimo, Klinger, Francesca Gioia, Annicchiarico-Petruzzelli, Margherita, Valensise, Herbert, Melino, Gerry, Candi, Eleonora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810856/ https://www.ncbi.nlm.nih.gov/pubmed/33452256 http://dx.doi.org/10.1038/s41467-020-20669-0 |
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