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A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Creatine is an organic compound used as fast phosphate energy buffer to recycle ATP, important in tissues with high energy demand such as muscle or brain. Creatine is taken from the diet or endogenously synthetized by the enzymes AGAT and GAMT, and specifically taken up by the transporter SLC6A8. De...

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Detalles Bibliográficos
Autores principales: Duran-Trio, Lara, Fernandes-Pires, Gabriella, Simicic, Dunja, Grosse, Jocelyn, Roux-Petronelli, Clothilde, Bruce, Stephen J., Binz, Pierre-Alain, Sandi, Carmen, Cudalbu, Cristina, Braissant, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810893/
https://www.ncbi.nlm.nih.gov/pubmed/33452333
http://dx.doi.org/10.1038/s41598-020-80824-x