Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model

Transgenic mouse models recapitulating Alzheimer’s disease (AD) pathology are pivotal in molecular studies and drug evaluation. In transgenic models selectively expressing amyloid-β (Aβ), thioflavin S (ThS), a fluorescent dye with β-sheet binding properties, is widely employed to observe amyloid pla...

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Detalles Bibliográficos
Autores principales: Shin, Jisu, Park, Sohui, Lee, HeeYang, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810901/
https://www.ncbi.nlm.nih.gov/pubmed/33452414
http://dx.doi.org/10.1038/s41598-021-81304-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810901/
https://www.ncbi.nlm.nih.gov/pubmed/33452414
http://dx.doi.org/10.1038/s41598-021-81304-6

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