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Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes

Smad transcription factors are the main downstream effectors of the Transforming growth factor β superfamily (TGFβ) signalling network. The DNA complexes determined here by X-ray crystallography for the Bone Morphogenetic Proteins (BMP) activated Smad5 and Smad8 proteins reveal that all MH1 domains...

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Detalles Bibliográficos
Autores principales: Ruiz, Lidia, Kaczmarska, Zuzanna, Gomes, Tiago, Aragon, Eric, Torner, Carles, Freier, Regina, Baginski, Blazej, Martin-Malpartida, Pau, de Martin Garrido, Natàlia, Marquez, José. A., Cordeiro, Tiago N., Pluta, Radoslaw, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810915/
https://www.ncbi.nlm.nih.gov/pubmed/33510867
http://dx.doi.org/10.1016/j.csbj.2020.12.044