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Exosomal miR-365a-5p derived from HUC-MSCs regulates osteogenesis in GIONFH through the Hippo signaling pathway

The pathogenesis of glucocorticoid (GC)-induced osteonecrosis of the femoral head (GIONFH) is still disputed, and abnormal bone metabolism caused by GCs may be an important factor. In vitro, Cell Counting Kit-8 (CCK-8) and 5-ethynyl-2′-deoxyuridine (EdU) staining were used to evaluate cellular proli...

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Detalles Bibliográficos
Autores principales: Kuang, Ming-jie, Zhang, Kai-hui, Qiu, Jie, Wang, An-bang, Che, Wen-wen, Li, Xiao-ming, Shi, Dong-li, Wang, Da-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810916/
https://www.ncbi.nlm.nih.gov/pubmed/33510944
http://dx.doi.org/10.1016/j.omtn.2020.12.006