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S‐Nitrosylation of Akt by organic nitrate delays revascularization and the recovery of cardiac function in mice following myocardial infarction

The effects of long‐term nitrate therapy are compromised due to protein S‐Nitrosylation, which is mediated by nitric oxide (NO). This study is to determine the role of Akt S‐Nitrosylation in the recovery of heart functions after ischaemia. In recombinant Akt protein and in HEK293 cells, NO donor dec...

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Detalles Bibliográficos
Autores principales: Li, Xiao‐Yan, Zhang, Hong‐Ming, An, Gui‐Peng, Liu, Mo‐Yan, Han, Shu‐Fang, Jin, Qun, Song, Ying, Lin, Yi‐Meng, Dong, Bo, Wang, Shuang‐Xi, Meng, Ling‐Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810919/
https://www.ncbi.nlm.nih.gov/pubmed/33128338
http://dx.doi.org/10.1111/jcmm.15263