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miR‐15a‐5p and miR‐21‐5p contribute to chemoresistance in cytogenetically normal acute myeloid leukaemia by targeting PDCD4, ARL2 and BTG2

Cytarabine and daunorubicin are old drugs commonly used in the treatment of acute myeloid leukaemia (AML). Refractory or relapsed disease because of chemotherapy resistance is a major issue. microRNAs (miRNAs) were incriminated in resistance. This study aimed to identify miRNAs involved in chemoresi...

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Detalles Bibliográficos
Autores principales: Vandewalle, Virginie, Essaghir, Ahmed, Bollaert, Emeline, Lenglez, Sandrine, Graux, Carlos, Schoemans, Hélène, Saussoy, Pascale, Michaux, Lucienne, Valk, Peter J. M., Demoulin, Jean‐Baptiste, Havelange, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810923/
https://www.ncbi.nlm.nih.gov/pubmed/33270982
http://dx.doi.org/10.1111/jcmm.16110