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Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer worldwide. Even if 5‐fluorouracil (5‐FU) is used as the first‐line chemotherapeutic drug, responsiveness is only 20‐30%. Acquired resistance to 5‐FU contributes to both poor patient prognosis and relapse, emphasizing the need to identify biomar...

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Detalles Bibliográficos
Autores principales: Blondy, Sabrina, Talbot, Hugo, Saada, Sofiane, Christou, Niki, Battu, Serge, Pannequin, Julie, Jauberteau, Marie‐Odile, Lalloué, Fabrice, Verdier, Mireille, Mathonnet, Muriel, Perraud, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810928/
https://www.ncbi.nlm.nih.gov/pubmed/33325631
http://dx.doi.org/10.1111/jcmm.15752