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Echinacoside reverses myocardial remodeling and improves heart function via regulating SIRT1/FOXO3a/MnSOD axis in HF rats induced by isoproterenol

Myocardial remodelling is important pathological basis of HF, mitochondrial oxidative stress is a promoter to myocardial hypertrophy, fibrosis and apoptosis. ECH is the major active component of a traditional Chinese medicine Cistanches Herba, plenty of studies indicate it possesses a strong antioxi...

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Detalles Bibliográficos
Autores principales: Ni, Yajuan, Deng, Jie, Liu, Xin, Li, Qing, Zhang, Juanli, Bai, Hongyuan, Zhang, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810933/
https://www.ncbi.nlm.nih.gov/pubmed/33314649
http://dx.doi.org/10.1111/jcmm.15904