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Cardiac fibroblast miR‐27a may function as an endogenous anti‐fibrotic by negatively regulating Early Growth Response Protein 3 (EGR3)
Pathological myocardial fibrosis and hypertrophy occur due to chronic cardiac stress. The microRNA‐27a (miR‐27a) regulates collagen production across diverse cell types and organs to inhibit fibrosis and could constitute an important therapeutic avenue. However, its impact on hypertrophy and cardiac...
Autores principales: | Teng, Lifeng, Huang, Yubing, Guo, Jun, Li, Bin, Lin, Jin, Ma, Lining, Wang, Yudai, Ye, Cong, Chen, Qianqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810947/ https://www.ncbi.nlm.nih.gov/pubmed/33215816 http://dx.doi.org/10.1111/jcmm.15814 |
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