Local delivery of simvastatin maintains tooth anchorage during mechanical tooth moving via anti‐inflammation property and AMPK/MAPK/NF‐kB inhibition

Simvastatin (SMV) could increase tooth anchorage during orthodontic tooth movement (OTM). However, previous studies on its bone‐specific anabolic and anti‐inflammation properties were based on static in vitro and in vivo conditions. AMPK is a stress‐activated kinase that protects tissue against seri...

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Detalles Bibliográficos
Autores principales: Xu, Lianyi, Sun, Xiaojuan, Zhu, Guangxun, Mao, Jing, Baban, Babak, Qin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810950/
https://www.ncbi.nlm.nih.gov/pubmed/33314684
http://dx.doi.org/10.1111/jcmm.16058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810950/
https://www.ncbi.nlm.nih.gov/pubmed/33314684
http://dx.doi.org/10.1111/jcmm.16058

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