SHP‐1 suppresses endotoxin‐induced uveitis by inhibiting the TAK1/JNK pathway

We investigated how Src‐homology 2‐domain phosphatase‐1 (SHP‐1) regulates the inflammatory response in endotoxin‐induced uveitis (EIU), and the signalling pathways involved. One week after intravitreal injection of short hairpin RNA targeting SHP‐1 or SHP‐1 overexpression lentivirus in rats, we indu...

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Detalles Bibliográficos
Autores principales: Zhuang, Xiaonan, Ma, Jun, Xu, Sisi, Sun, Zhongcui, Zhang, Rong, Zhang, Meng, Xu, Gezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810969/
https://www.ncbi.nlm.nih.gov/pubmed/33207073
http://dx.doi.org/10.1111/jcmm.15888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810969/
https://www.ncbi.nlm.nih.gov/pubmed/33207073
http://dx.doi.org/10.1111/jcmm.15888

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