CROP: a CRISPR/Cas9 guide selection program based on mapping guide variants

The off-target effect, in which DNA cleavage was conducted outside the targeted region, is a major problem which limits the applications of CRISPR/Cas9 genome editing system. CRISPR Off-target Predictor (CROP) is standalone program developed to address this problem by predicting off-target propensit...

Descripción completa

Detalles Bibliográficos
Autores principales: Aprilyanto, Victor, Aditama, Redi, Tanjung, Zulfikar Achmad, Utomo, Condro, Liwang, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811000/
https://www.ncbi.nlm.nih.gov/pubmed/33452424
http://dx.doi.org/10.1038/s41598-021-81297-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811000/
https://www.ncbi.nlm.nih.gov/pubmed/33452424
http://dx.doi.org/10.1038/s41598-021-81297-2

Ejemplares similares