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Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease

OBJECTIVE: Insulin resistance and altered hepatic mitochondrial function are central features of type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD), but the etiological role of these processes in disease progression remains unclear. Here we investigated the molecular links between i...

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Detalles Bibliográficos
Autores principales: Shannon, Chris E., Ragavan, Mukundan, Palavicini, Juan Pablo, Fourcaudot, Marcel, Bakewell, Terry M, Valdez, Ivan A., Ayala, Iriscilla, Jin, Eunsook S., Madesh, Muniswamy, Han, Xianlin, Merritt, Matthew E., Norton, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811046/
https://www.ncbi.nlm.nih.gov/pubmed/33359401
http://dx.doi.org/10.1016/j.molmet.2020.101154