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The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells

OBJECTIVE: Hormone secretion from metabolically active tissues, such as pancreatic islets, is governed by specific and highly regulated signaling pathways. Defects in insulin secretion are among the major causes of diabetes. The molecular mechanisms underlying regulated insulin secretion are, howeve...

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Detalles Bibliográficos
Autores principales: Wilhelmi, Ilka, Grunwald, Stephan, Gimber, Niclas, Popp, Oliver, Dittmar, Gunnar, Arumughan, Anup, Wanker, Erich E., Laeger, Thomas, Schmoranzer, Jan, Daumke, Oliver, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811047/
https://www.ncbi.nlm.nih.gov/pubmed/33359402
http://dx.doi.org/10.1016/j.molmet.2020.101151