Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes

BACKGROUND: During early HIV-1 infection, immunodominant T cell responses to highly variable epitopes lead to the establishment of immune escape virus variants. Here we assessed a type 1-polarized monocyte-derived dendritic cell (MDC1)-based approach to selectively elicit cytotoxic T lymphocyte (CTL...

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Detalles Bibliográficos
Autores principales: Garcia-Bates, Tatiana M., Palma, Mariana L., Anderko, Renee R., Hsu, Denise C., Ananworanich, Jintanat, Korber, Bette T., Gaiha, Gaurav D., Phanuphak, Nittaya, Thomas, Rasmi, Tovanabutra, Sodsai, Walker, Bruce D., Mellors, John W., Piazza, Paolo A., Kroon, Eugene, Riddler, Sharon A., Michael, Nelson L., Rinaldo, Charles R., Mailliard, Robbie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811131/
https://www.ncbi.nlm.nih.gov/pubmed/33450518
http://dx.doi.org/10.1016/j.ebiom.2020.103175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811131/
https://www.ncbi.nlm.nih.gov/pubmed/33450518
http://dx.doi.org/10.1016/j.ebiom.2020.103175

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