Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data

BACKGROUND: Copy number alterations (CNAs), due to their large impact on the genome, have been an important contributing factor to oncogenesis and metastasis. Detecting genomic alterations from the shallow-sequencing data of a low-purity tumor sample remains a challenging task. RESULTS: We introduce...

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Detalles Bibliográficos
Autores principales: Fan, Xinping, Luo, Guanghao, Huang, Yu S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811225/
https://www.ncbi.nlm.nih.gov/pubmed/33451280
http://dx.doi.org/10.1186/s12859-020-03924-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811225/
https://www.ncbi.nlm.nih.gov/pubmed/33451280
http://dx.doi.org/10.1186/s12859-020-03924-5

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