Network Pharmacology and Experimental Evidence Identify the Mechanism of Astragaloside IV in Oxaliplatin Neurotoxicity

BACKGROUND AND OBJECTIVE: Neurotoxicity is a common side effect of oxaliplatin; the effect of current drugs such as methylcobalamin and gabapentine is not obvious. Astragaloside IV (AS-IV) is an important active ingredient of Astragali Radix, which can protect the nervous system and inhibit tumor gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jingyu, Guan, Zhenbiao, Wang, Xiaowei, Sun, Dazhi, Li, Yongjin, Pei, Bei, Lu, Ye, Yuan, Liangxi, Zhang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811377/
https://www.ncbi.nlm.nih.gov/pubmed/33469263
http://dx.doi.org/10.2147/DDDT.S262818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811377/
https://www.ncbi.nlm.nih.gov/pubmed/33469263
http://dx.doi.org/10.2147/DDDT.S262818

Ejemplares similares