Targeted Deep Sequencing Reveals Unrecognized KIT Mutation Coexistent with NF1 Deficiency in GISTs

PURPOSE: NF1-deficient GISTs account for about 1% of gastrointestinal stromal tumors (GISTs) and are usually considered as a subtype of KIT/PDGFRA wild-type GISTs that have no detectable KIT and PDGFRA mutations. Some KIT/PDGFRA wild-type GISTs actually have cryptic KIT mutations (mKIT). So we inves...

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Detalles Bibliográficos
Autores principales: Wu, Jinchun, Zhou, Haiyan, Yi, Xiaoping, He, Qiongzhi, Lei, Tianxiang, Tan, Fengbo, Liu, Heli, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811451/
https://www.ncbi.nlm.nih.gov/pubmed/33469372
http://dx.doi.org/10.2147/CMAR.S280174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811451/
https://www.ncbi.nlm.nih.gov/pubmed/33469372
http://dx.doi.org/10.2147/CMAR.S280174

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