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p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides

METHODS: In this study, we used MTT assays to demonstrate that a combination of SPIO-Serum and wild-type p53 overexpression can reduce ovarian cancer cell viability in vitro. Prussian blue staining and iron assays were used to determine changes in intracellular iron concentration following SPIO-Seru...

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Detalles Bibliográficos
Autores principales: Zhang, Yunhan, Xia, Meihui, Zhou, Zizhen, Hu, Xiaoqing, Wang, Jiabin, Zhang, Meiyu, Li, Yi, Sun, Liankun, Chen, Fangfang, Yu, Huimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811475/
https://www.ncbi.nlm.nih.gov/pubmed/33469287
http://dx.doi.org/10.2147/IJN.S282489