Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis

Müller cells may have stem cell-like capability as they regenerate photoreceptor loss upon injury in some vertebrates, but not in mammals. Indeed, mammalian Müller cells undergo major cellular and molecular changes summarized as reactive gliosis. Transforming growth factor beta (TGFβ) isoforms are m...

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Detalles Bibliográficos
Autores principales: Conedera, Federica Maria, Quintela Pousa, Ana Maria, Presby, David Mikal, Mercader, Nadia, Enzmann, Volker, Tschopp, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811507/
https://www.ncbi.nlm.nih.gov/pubmed/32219603
http://dx.doi.org/10.1007/s10571-020-00830-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811507/
https://www.ncbi.nlm.nih.gov/pubmed/32219603
http://dx.doi.org/10.1007/s10571-020-00830-5

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