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Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis
Müller cells may have stem cell-like capability as they regenerate photoreceptor loss upon injury in some vertebrates, but not in mammals. Indeed, mammalian Müller cells undergo major cellular and molecular changes summarized as reactive gliosis. Transforming growth factor beta (TGFβ) isoforms are m...
Autores principales: | Conedera, Federica Maria, Quintela Pousa, Ana Maria, Presby, David Mikal, Mercader, Nadia, Enzmann, Volker, Tschopp, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811507/ https://www.ncbi.nlm.nih.gov/pubmed/32219603 http://dx.doi.org/10.1007/s10571-020-00830-5 |
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