Virtual screening of potentially endocrine-disrupting chemicals against nuclear receptors and its application to identify PPARγ-bound fatty acids

Nuclear receptors (NRs) are key regulators of energy homeostasis, body development, and sexual reproduction. Xenobiotics binding to NRs may disrupt natural hormonal systems and induce undesired adverse effects in the body. However, many chemicals of concerns have limited or no experimental data on t...

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Detalles Bibliográficos
Autores principales: Jaladanki, Chaitanya K., He, Yang, Zhao, Li Na, Maurer-Stroh, Sebastian, Loo, Lit-Hsin, Song, Haiwei, Fan, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811525/
https://www.ncbi.nlm.nih.gov/pubmed/32909075
http://dx.doi.org/10.1007/s00204-020-02897-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811525/
https://www.ncbi.nlm.nih.gov/pubmed/32909075
http://dx.doi.org/10.1007/s00204-020-02897-x

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