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Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced-nephropathy rats

The aim of this study was to investigate the effects of simvastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, on inflammation and glomerulosclerosis in Adriamycin (ADR)-induced nephropathy. Male Sprague-Dawley rats were randomly divided into control, ADR...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Li, Qiu, Wang, Lijia, Yang, Xiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811526/
https://www.ncbi.nlm.nih.gov/pubmed/18791746
http://dx.doi.org/10.1007/s00467-008-0933-8