Cargando…

22(R)-hydroxycholesterol for dopaminergic neuronal specification of MSCs and amelioration of Parkinsonian symptoms in rats

Oxysterols play vital roles in the human body, ranging from cell cycle regulation and progression to dopaminergic neurogenesis. While naïve human mesenchymal stem cells (hMSCs) have been explored to have neurogenic effect, there is still a grey area to explore their regenerative potential after in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Manisha, Jain, Manish, Bose, Samrat, Halder, Ashutosh, Nag, Tapas Chandra, Dinda, Amit Kumar, Mohanty, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811530/
https://www.ncbi.nlm.nih.gov/pubmed/33454721
http://dx.doi.org/10.1038/s41420-020-00351-6