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Proteolytic Processing of CD44 and Its Implications in Cancer

CD44 is a transmembrane glycoprotein expressed in several healthy and tumor tissues. Modifications in its structure contribute differently to the activity of this molecule. One modification that has provoked interest is the consecutive cleavage of the CD44 extracellular ectodomain by enzymes that be...

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Detalles Bibliográficos
Autores principales: Medrano-González, Priscila Anhel, Rivera-Ramírez, Osmar, Montaño, Luis Felipe, Rendón-Huerta, Erika P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811561/
https://www.ncbi.nlm.nih.gov/pubmed/33505471
http://dx.doi.org/10.1155/2021/6667735