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Design, synthesis, and biological evaluation of novel 5,6,7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors

OBJECTIVE(S): Microtubules have key roles in essential cellular processes such as mitosis, cell motion, and intracellular organelle transport. Increasing interest has been given to tubulin binding compounds after the introduction of taxanes into clinical oncology. The object of this study was synthe...

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Detalles Bibliográficos
Autores principales: Mirzaei, Salimeh, Eisvand, Farhad, Hadizadeh, Farzin, Mosaffa, Fatemeh, Ghodsi, Razieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811808/
https://www.ncbi.nlm.nih.gov/pubmed/33489025
http://dx.doi.org/10.22038/ijbms.2020.43303.10168