Cargando…
Design, synthesis, and biological evaluation of novel 5,6,7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors
OBJECTIVE(S): Microtubules have key roles in essential cellular processes such as mitosis, cell motion, and intracellular organelle transport. Increasing interest has been given to tubulin binding compounds after the introduction of taxanes into clinical oncology. The object of this study was synthe...
Autores principales: | Mirzaei, Salimeh, Eisvand, Farhad, Hadizadeh, Farzin, Mosaffa, Fatemeh, Ghodsi, Razieh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811808/ https://www.ncbi.nlm.nih.gov/pubmed/33489025 http://dx.doi.org/10.22038/ijbms.2020.43303.10168 |
Ejemplares similares
-
3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity
por: Mirzaei, Salimeh, et al.
Publicado: (2021) -
Corrigendum to “3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity”
por: Mirzaei, Salimeh, et al.
Publicado: (2022) -
In Silico Exploration of Novel Tubulin Inhibitors: A Combination of Docking and Molecular Dynamics Simulations, Pharmacophore Modeling, and Virtual Screening
por: Hadizadeh, Farzin, et al.
Publicado: (2022) -
Synthesis and biological evaluation of oxazinonaphthalene-3-one derivatives as potential anticancer agents and tubulin inhibitors
por: Mirzaei, Salimeh, et al.
Publicado: (2020) -
Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors
por: Mosaffa, Fatemeh, et al.
Publicado: (2021)