Maternal hypothyroidism during pregnancy alters the function of the retinol-binding protein 4-mediated mitochondrial permeability conversion pore in the kidneys of offspring rats

OBJECTIVES: To determine the role of the RBP4/PiC/SIRT3 signaling pathway in the opening of the mitochondria permeability transition pore (mPTP) in offspring rats with hypothyroidism during pregnancy. METHODS: Sixty Sprague-Dawley (SD) rats were employed in this study. Pregnancy was deemed successfu...

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Detalles Bibliográficos
Autores principales: Chen, Danyan, Li, Li, Ren, Fang, Huang, Rongxi, Gan, Hua, Deng, Huacong, Wang, Hongman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811836/
https://www.ncbi.nlm.nih.gov/pubmed/33503180
http://dx.doi.org/10.6061/clinics/2021/e2096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811836/
https://www.ncbi.nlm.nih.gov/pubmed/33503180
http://dx.doi.org/10.6061/clinics/2021/e2096

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