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Maternal hypothyroidism during pregnancy alters the function of the retinol-binding protein 4-mediated mitochondrial permeability conversion pore in the kidneys of offspring rats
OBJECTIVES: To determine the role of the RBP4/PiC/SIRT3 signaling pathway in the opening of the mitochondria permeability transition pore (mPTP) in offspring rats with hypothyroidism during pregnancy. METHODS: Sixty Sprague-Dawley (SD) rats were employed in this study. Pregnancy was deemed successfu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Faculdade de Medicina / USP
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811836/ https://www.ncbi.nlm.nih.gov/pubmed/33503180 http://dx.doi.org/10.6061/clinics/2021/e2096 |