Interleukin‐6 neutralization ameliorates symptoms in prematurely aged mice

Hutchinson–Gilford progeria syndrome (HGPS) causes premature aging in children, with adipose tissue, skin and bone deterioration, and cardiovascular impairment. In HGPS cells and mouse models, high levels of interleukin‐6, an inflammatory cytokine linked to aging processes, have been detected. Here,...

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Detalles Bibliográficos
Autores principales: Squarzoni, Stefano, Schena, Elisa, Sabatelli, Patrizia, Mattioli, Elisabetta, Capanni, Cristina, Cenni, Vittoria, D'Apice, Maria Rosaria, Andrenacci, Davide, Sarli, Giuseppe, Pellegrino, Valeria, Festa, Anna, Baruffaldi, Fabio, Storci, Gianluca, Bonafè, Massimiliano, Barboni, Catia, Sanapo, Mara, Zaghini, Anna, Lattanzi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811841/
https://www.ncbi.nlm.nih.gov/pubmed/33393189
http://dx.doi.org/10.1111/acel.13285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811841/
https://www.ncbi.nlm.nih.gov/pubmed/33393189
http://dx.doi.org/10.1111/acel.13285

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