Antiallergic drug desloratadine as a selective antagonist of 5HT(2A) receptor ameliorates pathology of Alzheimer's disease model mice by improving microglial dysfunction

Alzheimer's disease (AD) is a progressively neurodegenerative disease characterized by cognitive deficits and alteration of personality and behavior. As yet, there is no efficient treatment for AD. 5HT(2A) receptor (5HT(2A)R) is a subtype of 5HT(2) receptor belonging to the serotonin receptor f...

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Detalles Bibliográficos
Autores principales: Lu, Jian, Zhang, Chuzhao, Lv, Jianlu, Zhu, Xialin, Jiang, Xingwu, Lu, Weiqiang, Lu, Yin, Tang, Zongxiang, Wang, Jiaying, Shen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811850/
https://www.ncbi.nlm.nih.gov/pubmed/33369003
http://dx.doi.org/10.1111/acel.13286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811850/
https://www.ncbi.nlm.nih.gov/pubmed/33369003
http://dx.doi.org/10.1111/acel.13286

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