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Inhibition of Dectin-1 on Dendritic Cells Prevents Maturation and Prolongs Murine Islet Allograft Survival

INTRODUCTION: The ability of dendritic cells (DCs) to initiate an immune response or induce immune tolerance depends on their maturation status. Dendritic-cell-associated C-type lectin 1 (Dectin-1) plays a key role in the differentiation, activation, and maturation of DCs. Therefore, we hypothesized...

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Detalles Bibliográficos
Autores principales: Ren, Ao, Li, Zhongqiu, Zhang, Xuzhi, Deng, Ronghai, Ma, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812029/
https://www.ncbi.nlm.nih.gov/pubmed/33469336
http://dx.doi.org/10.2147/JIR.S287453